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2B4 / SLAMF4 / CD244 抗体, 鼠单抗

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     2B4/SLAMF4 抗体产品信息
    免疫原:Recombinant Human 2B4 / SLAMF4 / CD244 Protein (Catalog#10042-H08H)
    克隆号:3F3A6
    Ig 类型:Mouse IgG1
    浓度:
    内毒素:
    缓冲液:0.2 μm filtered solution in PBS with 5% trehalose
    抗体制备方法:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human 2B4 / SLAMF4 / CD244 (rh 2B4 / SLAMF4 / CD244; Catalog#10042-H08H; NP_057466.1; Met 1-Arg 221). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
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    2B4 / CD244 研究背景

    The CD244 antigen

     2B4 / CD244 参考资料
  • Nakajima H, et al. (2000) 2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism. Hum Immunol. 61(1): 39-43.
  • Chuang SS, et al. (2001) 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways. J Immunol. 167(11): 6210-6.
  • McNerney ME, et al. (2005) 2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells. Mol Immunol. 42(4): 489-94.
  • Mathew SO, et al. (2009) Functional role of human NK cell receptor 2B4 (CD244) isoforms. Eur J Immunol. 39(6): 1632-41.
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    货号: 10042-MM02-200
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    Datasheet & Documentation

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