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人 2B4 / SLAMF / CD244 蛋白 (His 标签)

  • Human 2B4 / SLAMF / CD244 Protein (His Tag) SDS-PAGE
产品数据评论相关产品实验方法
 2B4/SLAMF4 蛋白产品信息
分子别称:2B4,NAIL,NKR2B4,Nmrk,SLAMF4
蛋白构建:A DNA sequence encoding the extracellular domain (Met 1-Arg 221) of human 2B4 (NP_057466.1) was expressed, with a polyhistidine tag at the C-terminus.
分子种属:Human
表达宿主:Human Cells
运输说明:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
 2B4/SLAMF4 蛋白质控检测
纯度:> 95 % as determined by SDS-PAGE
生物活性:Measured by its binding ability in a functional ELISA . Immobilized human 2B4 at 2 μg/ml (100 μl/well) can bind human CD48. The EC50 of human CD48 is 0.39 μg/ml .
内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
稳定性:Samples are stable for up to twelve months from date of receipt at -70℃
预测N端:Cys 22
分子量:The recombinant 2B4 comprises 211 amino acids and predicts a molecular mass of 23.8 kDa. As a result of glycosylation, the rh 2B4 protein migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
缓冲液:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
 2B4/SLAMF4 蛋白使用指导
储存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶条件:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
 2B4/SLAMF4 蛋白SDS-PAGE
Human 2B4 / SLAMF / CD244 Protein (His Tag) SDS-PAGE

2B4/SLAMF4 相关信号通路

    Other 2B4/SLAMF4 蛋白 Products
    10042-H08H
    2B4 / CD244 研究背景

    The CD244 antigen

     2B4 / CD244 参考资料
  • Nakajima H, et al. (2000) 2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism. Hum Immunol. 61(1): 39-43.
  • Chuang SS, et al. (2001) 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways. J Immunol. 167(11): 6210-6.
  • McNerney ME, et al. (2005) 2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells. Mol Immunol. 42(4): 489-94.
  • Mathew SO, et al. (2009) Functional role of human NK cell receptor 2B4 (CD244) isoforms. Eur J Immunol. 39(6): 1632-41.
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    货号: 10042-H08H-50
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    产品数据可能随批次变化,最新数据请详见随货说明书。
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”