快速订购

4-1BBL / CD137L 抗体, 兔多抗

    产品数据评论相关产品实验方法
    大鼠 TNFSF9 抗体产品信息
    免疫原:Recombinant Rat 4-1BBL / CD137L protein (Catalog#80166-R07H)
    克隆号:
    Ig 类型:Rabbit IgG
    浓度:
    内毒素:
    缓冲液:0.2 μm filtered solution in PBS
    抗体制备方法:Produced in rabbits immunized with purified, recombinant Rat 4-1BBL / CD137L (rh TNFSF9; Catalog#80166-R07H; Q80WE6; Pro106-Gly308). Total IgG was purified by Protein A affinity chromatography.
    Other TNFSF9 抗体 Products
    CD137L/4-1BBL/TNFSF9 研究背景

    4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In additon, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

    Immune Checkpoint
    Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: FCM Antibodies
    Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

    Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    大鼠 CD137L/4-1BBL/TNFSF9 参考资料
  • Cheung CT, (2007) Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Lab Invest. 87(7): 651-61.
  • Wang C, et al. (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev. 229(1): 192-215.
  • Habib-Agahi M, et al. (2009) 4-1BBL costimulation retrieves CD28 expression in activated T cells. Cell Immunol. 256(1-2): 39-46.
  • Product nameProduct name
    Size / Price
    货号: 80166-RP01-400
    目录价: 
    单价:      (You Save: )

    Datasheet & Documentation

    产品数据可能随批次变化,最新数据请详见随货说明书。
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”