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4E-BP1/EIF4EBP1

4E-BP1/EIF4EBP1 蛋白&抗体

Entrez Gene Summary for 4E-BP1/EIF4EBP1基因Entrez概述


This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

OMIM-Description for 4E-BP1/EIF4EBP1OMIM概述


inhibited the mTORC1 (601231) pathway in cells lacking EIF4EBP1, EIF4EBP2 (602224), and EIF4EBP3 (603483) and analyzed the effects on cell size, cell proliferation, and cell cycle progression. Although the EIF4EBPs had no effect on cell size, they inhibited cell proliferation by selectively inhibiting the translation of mRNAs that encode proliferation-promoting proteins and proteins involved in cell cycle progression. Thus, Dowling et al. (2010) concluded that control of cell size and cell cycle progression appear to be independent in mammalian cells, whereas in lower eukaryotes, EIF4E binding proteins influence both cell growth and proliferation.

.zh= 维基百科概述4E-BP1/EIF4EBP1


EIF4EBP1

4E-BP1/EIF4EBP1 别称

4E-BP1/EIF4EBP1 Related Products

4E-BP1/EIF4EBP1 Proteins

Product nameProduct name
人 4E-BP1 / EIF4EBP1 蛋白 (His 标签)

4E-BP1/EIF4EBP1 Antibodies

Product nameProduct name
4E-BP1 / EIF4EBP1 抗体, 兔单抗4E-BP1 / EIF4EBP1 抗体, 鼠单抗4E-BP1 / EIF4EBP1 抗体, 鼠单抗4E-BP1 / EIF4EBP1 抗体, 兔单抗4E-BP1 / EIF4EBP1 抗体 (FITC), 鼠单抗4E-BP1 / EIF4EBP1 抗体 (PE), 鼠单抗4E-BP1 / EIF4EBP1 抗体, 兔多抗4E-BP1 / EIF4EBP1 抗体, 兔单抗4E-BP1 / EIF4EBP1 抗体, 兔多抗, 抗原亲和纯化

4E-BP1/EIF4EBP1 cDNA Clones

Product nameProduct name
人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-GFPSpark 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-His 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-Myc 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-His 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-Myc 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-Flag 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-OFPSpark 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-GFPSpark 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-HA 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA(克隆载体)人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-HA 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-OFPSpark 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-HA 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-Myc 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-His 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体)Rat 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-HA 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-His 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-Flag 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA(克隆载体)人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-Flag 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-Flag 标签小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体)小鼠 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签人 4E-BP1/EIF4EBP1 基因ORF全长cDNA克隆(表达载体), N-Myc 标签

4E-BP1/EIF4EBP1 ELISA

Product nameProduct name
请注意:所有产品都是“仅用于科研,而不是为了用于诊断或治疗用途”