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AARSD1 抗体, 鼠单抗

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     AARSD1 抗体产品信息
    免疫原:Recombinant Human AARSD1 Protein (Catalog#14280-H07E )
    克隆号:01
    Ig 类型:Mouse IgG1
    浓度:
    内毒素:
    缓冲液:0.2 μm filtered solution in PBS
    抗体制备方法:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AARSD1 (rh AARSD1; Catalog#14280-H07E; Q9BTE6-2; Thr176-Glu525). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
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    AARSD1 研究背景

    AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcript variants have been described for AARSD1: NM_025267.3, NM_001136042.2, NM_001142653.1 and NM_001142654.1. It has been determined that the latter two variants represent a distinct upstream locus, which is now represented by GeneID:100885848 (PTGES3L), while the former two variants represent readthrough transcripts between PTGES3L and this locus (AARSD1). The readthrough locus (PTGES3L-AARSD1) is now represented by GeneID:100885850.

     AARSD1 参考资料
  • Tatham MH, et al. (2011) Comparative proteomic analysis identifies a role for SUMO in protein quality control. Oncogene. 19(17):2120-8.
  • Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.
  • Udeshi ND, et al. (2012) Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Mol Cell Proteomics. 11(5):148-59.
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    货号: 14280-MM01-200
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