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GABA-transaminase/ABAT  抗体

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GABA-transaminase/ABAT 相关研究领域

GABA-transaminase/ABAT 相关信号通路

    GABA-transaminase/ABAT 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    GABA-transaminase/ABAT 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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    GABA-transaminase/ABAT 概述&蛋白信息

    GABA-transaminase/ABAT 研究背景

    催化活性: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.; (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.
    辅因子: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000250|UniProtKB:P80147}; Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:49601; Evidence={ECO:0000250|UniProtKB:P80147}; ; Note=Binds 1 [2Fe-2S] cluster per homodimer. {ECO:0000250|UniProtKB:P80147};
    亚单位结构: Homodimer; disulfide-linked. {ECO:0000269|PubMed:15528998}.
    亚细胞定位: Mitochondrion matrix.
    组织特异性: Liver > pancreas > brain > kidney > heart > placenta.
    相关疾病 : DISEASE: GABA transaminase deficiency (GABATD) [MIM:613163]: An enzymatic deficiency resulting in psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. {ECO:0000269|PubMed:10407778}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    相似的序列: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}.
    General information above from UniProt

    GABA-transaminase/ABAT 别称

    GABAT,NPD009,GABA-AT, [homo-sapiens]
    I54,Gabat,Gabaat,Gm9851,Laibat,X61497,AI255750,9630038C02Rik,ENSMUSG00000051226, [mus-musculus]

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