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GABA-transaminase/ABAT  蛋白

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GABA-transaminase/ABAT 相关信号通路

GABA-transaminase/ABAT 相关蛋白、抗体、cDNA基因、ELISA试剂盒

GABA-transaminase/ABAT 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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GABA-transaminase/ABAT 概述&蛋白信息

GABA-transaminase/ABAT 研究背景

催化活性: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
(S)-3-amino-2-methylpropanoate + 2- oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.
辅因子: Pyridoxal phosphate.
亚单位结构: Homodimer; disulfide-linked.
亚细胞定位: Mitochondrion matrix.
组织特异性: Liver > pancreas > brain > kidney > heart > placenta.
相关疾病 : GABA transaminase deficiency (GABATD) [MIM:613163]: An enzymatic deficiency resulting in psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似的序列: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
General information above from UniProt

GABA-transaminase/ABAT 别称

GABAT,NPD009,GABA-AT, [homo-sapiens]
I54,Gabat,Gabaat,Gm9851,Laibat,X61497,AI255750,9630038C02Rik,ENSMUSG00000051226, [mus-musculus]

GABA-transaminase/ABAT 相关文献

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