BCRP / ABCG2 cDNA ORF Clone in Cloning Vector, Rhesus

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BCRP / ABCG2 cDNA ORF Clone in Cloning Vector, Rhesus: 产品信息

基因
种属
Rhesus
NCBI 参考序列号
基因长度
1965 bp
序列特征
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 166C/G(R56G), 1840G/A(A614Y). Please check the sequence information before order.
产品特征
Full length Clone DNA of Rhesus ATP-binding cassette, sub-family G (WHITE), member 2.
质粒
载体
测序引物
SP6 and T7 or M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

BCRP / ABCG2 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

BCRP / ABCG2 背景信息

ATP-binding cassette subfamily G member 2 (ABCG2), a member of the ABC transporter superfamily proteins. the expression of ABCG2 is related to tumorigenic cancer stem cells (CSC) in several cancers, mediates multidrug resistance (MDR) by transporting substrate anticancer drugs out of cancer cells and decreasing their intracellular accumulation. ABCB1 and ABCG2 are efflux transporters which have a major impact on the pharmacological behavior of numerous drugs. They are expressed in the intestine, liver, kidney, BBB and placenta. It has become evident that ABCB1 and ABCG2 modify the pharmaco/toxicokinetics in the placenta and fetus and may consequently affect the outcome of pregnancy.
全称
ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
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