ABI2 Protein

ABI2 Protein Overview

ABI2 reagents

The ABL protein (ABL1; 189980) is the cellular homolog of the Abl oncogene product of Abelson murine leukemia virus. ABL is a tyrosine kinase that may regulate signal transduction events in the cytoplasm and processes in the nucleus. The transforming Abl proteins are constitutively active tyrosine kinases primarily localized in the cytoplasm. They are repressed by SH3 domains and possibly by other regions.

ABI2 protein family

Belongs to the ABI family.

ABI2 protein name

Recommended name
Abl interactor 2
Aliases
ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2
Alternative name
Abelson interactor 2 Abi-2 Abl-binding protein 3 AblBP3 Arg-binding protein 1 ArgBP1

ABI2 Protein Sequence

Species Human ABI2 protein
Length 513
Mass (Da) 55663
Sequence Human ABI2 protein sequence
Species Mouse ABI2 protein
Length 446
Mass (Da) 49387
Sequence Mouse ABI2 protein sequence
Species
Length
Mass (Da)
Sequence

ABI2 Protein Molecular Weight & PI

Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-513 Abl interactor 2.

Molecular weight (Da)

55663.24

Theoretical pI

5.81

ABI2 Protein Structure

The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
Deposited
2013-10-15   Released:  2014-02-05
Deposition Author(s)
Chen, Z.C.
Organism(s)
Homo sapiens
Expression System
Escherichia coli, Spodoptera frugiperda
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.4300 Å
R-Value Free
0.209
R-Value Work
0.189
4N78 From PDB

Human ABI2 protein Secondary structure

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