ABP1 / AOC1 cDNA ORF Clone in Cloning Vector, Human

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ABP1 / AOC1 cDNA ORF Clone in Cloning Vector, Human: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
2256 bp
序列特征
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 1993C/T not causing the amino acid variation.
产品特征
Full length Clone DNA of Human amiloride binding protein 1 (amine oxidase (copper-containing)).
质粒
载体
测序引物
SP6 and T7 or M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

ABP1 / AOC1 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

关于 ABP1 / AOC1的更多信息

Entrez Gene ID

ABP1 / AOC1 cDNA ORF Clone in Cloning Vector, Human: 别称

ABP cDNA ORF Clone, Human; ABP1 cDNA ORF Clone, Human; DAO cDNA ORF Clone, Human; DAO1 cDNA ORF Clone, Human; KAO cDNA ORF Clone, Human

ABP1 / AOC1 背景信息

Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under control of the proximal AOC1 promoter was significantly enhanced by co-transfection of a WT1 expression construct. Binding of WT1 protein to a cis-regulatory element in the AOC1 promoter was confirmed by electrophoretic mobility shift assay and chromatin immunoprecipitation. WT1-dependent control of polyamine breakdown, which is mediated by changes in AOC1 expression, has a role in kidney organogenesis.
全称
amine oxidase, copper containing 1

ABP1 / AOC1 cDNA ORF Clone, Human, 相关产品

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