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ADSL / Adenylosuccinate Lyase 抗体, 兔单抗

  • Human ASGPR1  Immunoprecipitation(IP) 8018
  • ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
  • ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
  • ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
  • ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Western blot
  • ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunoprecipitation
  • Human ADSL / Adenylosuccinate Lyase Immunofluorescence(IF) 16033
产品数据评论相关产品实验方法
 ADSL 抗体产品信息
免疫原:Recombinant Human ADSL / Adenylosuccinate Lyase protein (Catalog#11287-H07E)
克隆号:007
Ig 类型:Rabbit IgG
浓度:
内毒素:
缓冲液:0.2 μm filtered solution in PBS
抗体制备方法:This antibody was obtained from a rabbit immunized with purified, recombinant Human ADSL / Adenylosuccinate Lyase (rh ADSL / Adenylosuccinate Lyase; Catalog#11287-H07E; P30566-1; Met1-Leu484).
 ADSL 抗体WB实验图片
 ADSL 抗体IHC实验图片
ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
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Caption:
Immunochemical staining of human ADSL in human ovarian cancer with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections).
ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
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Caption:
Immunochemical staining of human ADSL in human small intestine with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections).
ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
[点击查看大图]
Caption:
Immunochemical staining of human ADSL in human thyroid with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections).
 ADSL 抗体IP实验图片
Other ADSL 抗体 Products
Flow cytometric analysis of Mouse LILRB3(CD85a) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse LILRB3(CD85a), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
ADSL / Adenylosuccinate Lyase 研究背景

Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotides, both of which involve the _-elimination of fumarate to produce either aminoimidazole carboxamide ribotide from SAICAR or AMP from S-AMP. The Adenylosuccinate lyase deficiency is a rare autosomal recessive metabolic disorder characterized by the present of SAICA riboside and succinyladenosine (S-Ado). ADSL defect in different patients is often caused by different mutations to the enzyme.

 ADSL / Adenylosuccinate Lyase 参考资料
  • Nassogne M, et al. (2000) Adenylosuccinase deficiency: an unusual cause of early-onset epilepsy associated with acquired microcephaly. Brain and development. 22 (6): 383-6.
  • Sivendran S, et al. (2004) Two novel mutant human adenylosuccinate lyases (ASLs) associated with autism and characterization of the equivalent mutant Bacillus subtilis ASL. J Biol Chem. 279 (51): 53789-97.
  • Lee TT, et al. (1999) His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis. Biochemistry. 38 (1): 22-32.
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    货号: 11287-R007-100
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    Datasheet & Documentation

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