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APLP1 / Amyloid-like 蛋白 1 抗体, 兔多抗, 抗原亲和纯化

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     APLP1 抗体产品信息
    免疫原:Recombinant Human APLP1 / Amyloid-like protein 1 protein (Catalog#13716-H08H)
    克隆号:
    Ig 类型:Rabbit IgG
    浓度:
    内毒素:
    缓冲液:0.2 μm filtered solution in PBS
    抗体制备方法:Produced in rabbits immunized with purified, recombinant Human APLP1 / Amyloid-like protein 1 (rh APLP1 / Amyloid-like protein 1; Catalog#13716-H08H; P51693-1; Met1-Glu580). APLP1 / Amyloid-like protein 1 specific IgG was purified by Human APLP1 / Amyloid-like protein 1 affinity chromatography.
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    APLP1 / Amyloid-like protein 1 研究背景

    APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

     APLP1 / Amyloid-like protein 1 参考资料
  • Wasco W. et al., 1993, Genomics. 15 (1): 237-9.
  • Needham BE. et al., 2008, J Pathol. 215 (2): 155-63.
  • Bayer TA. et al., 2000, Mol Psychiatry. 4 (6): 524-8.
  • Lee S. et al., 2011, Biochemistry. 50 (24): 5453-64.
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    货号: 13716-T16-200
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