Anti-APLP1 Antibody

Cat: 13716-T16

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Anti-APLP1 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-APLP1 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human APLP1
Immunogen
Recombinant Human APLP1 / Amyloid-like protein 1 protein (Catalog#13716-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human APLP1 / Amyloid-like protein 1 (rh APLP1 / Amyloid-like protein 1; Catalog#13716-H08H; P51693-1; Met1-Glu580). APLP1 / Amyloid-like protein 1 specific IgG was purified by Human APLP1 / Amyloid-like protein 1 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Anti-APLP1 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-APLP1 Antibody Alternative Names

Anti-APLP Antibody

APLP1 Background Information

APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

Full Name
amyloid beta (A4) precursor-like protein 1
References
  • Wasco W. et al., 1993, Genomics. 15 (1): 237-9.
  • Needham BE. et al., 2008, J Pathol. 215 (2): 155-63.
  • Bayer TA. et al., 2000, Mol Psychiatry. 4 (6): 524-8.
  • Lee S. et al., 2011, Biochemistry. 50 (24): 5453-64.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-APLP1 Antibody Rabbit Polyclonal ELISA,IHC-P 51730-T24
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