Anti-APLP1 Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human APLP1 / Amyloid-like protein 1 protein (Catalog#13716-H08H)
Produced in rabbits immunized with purified, recombinant Human APLP1 / Amyloid-like protein 1 (rh APLP1 / Amyloid-like protein 1; Catalog#13716-H08H; P51693-1; Met1-Glu580). APLP1 / Amyloid-like protein 1 specific IgG was purified by Human APLP1 / Amyloid-like protein 1 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-APLP1 Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-APLP1 Antibody Alternative Names
APLP1 Background Information
APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
amyloid beta (A4) precursor-like protein 1
Wasco W. et al., 1993, Genomics. 15 (1): 237-9. Needham BE. et al., 2008, J Pathol. 215 (2): 155-63. Bayer TA. et al., 2000, Mol Psychiatry. 4 (6): 524-8. Lee S. et al., 2011, Biochemistry. 50 (24): 5453-64.