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ApoM / Apolipoprotein M  蛋白

All ApoM Reagents

表达宿主: Yeast  
  • Slide 1
13495-H08Y-100
13495-H08Y-50
100 µg 
50 µg 
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表达宿主: Human Cells  
  • Slide 1
13495-H02H-20
13495-H02H-50
20 µg 
50 µg 
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ApoM / Apolipoprotein M 相关信号通路

ApoM / Apolipoprotein M 相关蛋白、抗体、cDNA基因、ELISA试剂盒

ApoM / Apolipoprotein M 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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ApoM / Apolipoprotein M 概述&蛋白信息

ApoM / Apolipoprotein M 研究背景

基因概述: The protein encoded by this APOM gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. Apolipoprotein M is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
General information above from NCBI
亚细胞定位: Secreted. Note=Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL).
组织特异性: Plasma protein. Expressed in liver and kidney.
相似的序列: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.C
General information above from UniProt

ApoM (apolipoprotein M) is an apolipoprotein and member of the lipocalin protein family. The lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They have an eight-stranded, antiparallel, symmetrical _-barrel fold, which is in essence a beta sheet which has been rolled into a cylindrical shape. Inside this barrel is located a ligand binding site. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins have been associated with many biological processes, among them immune response, pheromone transport, biological prostaglandin synthesis, retinoid binding, and cancer cell interactions. Lipocalins are comparatively small in size, and are thus less complicated to study as opposed to large, bulky proteins. They can also bind to various ligands for different biological purposes. ApoM is associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. ApoM is involved in lipid transport and can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.

ApoM / Apolipoprotein M 别称

G3a,NG20,apo-M,HSPC336, [homo-sapiens]
apo-M,DADB-127H9.5,G3a,HSPC336,NG20,NG20-like protein,protein G3a, [human]
apo-M,G3a,NG20, [mouse]
G3a,NG20,1190010O19Rik, [mus-musculus]

ApoM / Apolipoprotein M 相关文献

  • Xu N, et al. (1999) A novel human apolipoprotein (apoM). J Biol Chem. 274(44):31286-90.
  • Duan J, et al. (2001) Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis. FEBS Lett. 49 (1-2):127-32.
  • Albertella MR, et al. (1997) Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B). Genomics. 36(2):240-51.
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