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Adipsin / Complement Factor D 抗体, 兔单抗

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Mouse CFD 抗体产品信息
免疫原:Recombinant Mouse Adipsin / Complement Factor D protein (Catalog#50539-M08H)
克隆号:121
Ig 类型:Rabbit IgG
浓度:
内毒素:
缓冲液:0.2 μm filtered solution in PBS
抗体制备方法:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Adipsin / Complement Factor D (rh Adipsin / Complement Factor D; Catalog#50539-M08H; P03953-2; Met1-Ser258).
Mouse CFD 抗体使用指导
特异性:Mouse Adipsin / Complement Factor D
No cross-reactivity in ELISA with
Human CFH
Human CFAD
推荐应用:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse Adipsin / Complement Factor D. The detection limit for Mouse Adipsin / Complement Factor D is 0.00245 ng/well.

储存方法:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other CFD 抗体 Products
FACTOR D/Adipsin 研究背景

Mouse complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to the peptidase S1 family. CFD / Adipsin contains one peptidase S1 domain. Complement factor D ( CFD / Adipsin ) is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Complement factor D ( CFD / Adipsin ) has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Complement factor D ( CFD / Adipsin ) cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D ( CFD / Adipsin ) is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency (CFD deficiency) which predisposes to invasive meningococcal disease.

Mouse FACTOR D/Adipsin 参考资料
  • Volanakis JE, et al.,1996, Protein Sci. 5 (4): 553-64.
  • Searfoss,G.H et al., 2003, J Biol Chem. 278 (46):46107-16.
  • Ukkola,O. et al., 2003, Eur J Clin Nutr. 57 (9):1073-8.
  • Ronti T, et al., 2006, Clin. Endocrinol. (Oxf) 64 (4): 355-65.
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    货号: 50539-R121-50
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