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BMP-2 抗体, 兔单抗

  • BMP-2 Antibody, Rabbit MAb, Immunofluorescence
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 BMP2 抗体产品信息
免疫原:Recombinant Human BMP-2 protein (Catalog#10426-HNAE)
克隆号:110
Ig 类型:Rabbit IgG
浓度:
内毒素:
缓冲液:0.2 μm filtered solution in PBS with 5% trehalose
抗体制备方法:This antibody was obtained from a rabbit immunized with purified, recombinant Human BMP-2 (rh BMP-2; Catalog#10426-HNAE; NP_001191.1; Gln283-Arg396).
 BMP2 抗体IF实验图片
BMP-2 Antibody, Rabbit MAb, Immunofluorescence
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Caption:
Immunofluorescence staining of Human BMP2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human BMP2 monoclonal antibody (15 µg/ml) at 37℃ 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
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      BMP-2 研究背景

      BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

       BMP-2 参考资料
    • Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6.
    • Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.
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      Size / Price
      货号: 10426-R110-50
      目录价: 
      单价:      (You Save: )

      Datasheet & Documentation

      产品数据可能随批次变化,最新数据请详见随货说明书。
      请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”