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CCL16 / HCC-4 / NCC4  蛋白,抗体,试剂盒,cDNA克隆

表达宿主: E. coli  
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表达宿主: Yeast  
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CCL16 / HCC-4 / NCC4 相关研究领域

CCL16 / HCC-4 / NCC4 相关信号通路

    CCL16 / HCC-4 / NCC4 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    CCL16 / HCC-4 / NCC4 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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    CCL16 / HCC-4 / NCC4 概述&蛋白信息

    CCL16 / HCC-4 / NCC4 相关资讯

    CCL16 / HCC-4 / NCC4 研究背景

    亚细胞定位: Secreted.
    组织特异性: Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
    诱导: By IL10/interleukin-10.
    相似的序列: Belongs to the intercrine beta (chemokine CC) family. {ECO:0000305}.
    General information above from UniProt

    CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was transfected with human CCL16 cDNA and, in comparison with other cytokines, was shown to be the faster inducer of systemic immune response due to massive, prompt infiltration of leukocytes.

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    CCL16 / HCC-4 / NCC4 别称

    chemokine (C-C motif) ligand 16,CCL16,CKb12,HCC-4,ILINCK,LCC-1,LEC,LMC,Mtn-1,NCC-4,NCC4,SCYA16,SCYL4,C-C motif chemokine 16,IL-10-inducible chemokine,chemokine CC-4,chemokine LEC,liver CC chemokine-1,liver-expressed chemokine,lymphocyte and monocyte chemoattractant,monotactin-1,new CC chemokine 4,small inducible cytokine subfamily A (Cys-Cys), member 16,small-inducible cytokine A16, [human]

    CCL16 / HCC-4 / NCC4 相关文献

  • Guiducci C, Di Carlo E, Parenza M, et al. Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor[J]. The Journal of Immunology, 2004, 172(7): 4026-4036.
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