MCP-1 / CCL2 Protein, Mouse, Recombinant (His Tag)

Cat: 50368-M08B

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MCP-1 / CCL2 Protein, Mouse, Recombinant (His Tag) 产品信息

Purity
> 80 % as determined by SDS-PAGE
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the mouse CCL2 (NP_035463.1) (Met1-Asn148) was expressed with a C-terminal polyhistidine tag.
Accession#
Expressed Host
Baculovirus-Insect cells
Species
Mouse
Predicted N Terminal
Gln 24
Molecule Mass
The recombinant mouse CCL2 comprises 135 amino acids and has a predicted molecular mass of 15.2 kDa. The apparent molecular mass of the protein is approximately 27 kDa in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

MCP-1 / CCL2 Protein, Mouse, Recombinant (His Tag) in SDS-PAGE

Mouse MCP-1/CCL2 Protein 11599

MCP-1 / CCL2 Protein, Mouse, Recombinant (His Tag) Alternative Names

AI323594 Protein, Mouse;HC11 Protein, Mouse;JE Protein, Mouse;MCAF Protein, Mouse;MCP-1 Protein, Mouse;MCP1 Protein, Mouse;Scya2 Protein, Mouse;Sigje Protein, Mouse;SMC-CF Protein, Mouse

MCP-1 / CCL2 Background Information

Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection [7–9]. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
chemokine (C-C motif) ligand 2
References
  • Vásquez-Loarte T, Trubnykova M, Guio H. Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model. BMC Genetics. 2015;16:128.
  • Other MCP-1 / CCL2 Proteins

    Human MCP-1 / CCL2 Proteins

    Product Name Cat.No.
    MCP-1 / CCL2 Protein, Human, Recombinant (His Tag) 10134-H08Y
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