Nectin-2 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)
All Nectin-2 reagents are produced in house and quality controlled, including 12 Nectin-2 Antibody, 2 Nectin-2 ELISA, 39 Nectin-2 Gene, 2 Nectin-2 IP Kit, 6 Nectin-2 Lysate, 6 Nectin-2 Protein, 3 Nectin-2 qPCR. All Nectin-2 reagents are ready to use.
All Nectin-2 Reagents
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Nectin-2 Protein (6)Recombinant Nectin-2 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-cleavage, C-human IgG1-Fc.
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Nectin-2 Antibody (12)Nectin-2 antibodies are validated with different applications, which are FCM, ELISA, IHC-P, WB, IP, ELISA(Cap).
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Nectin-2 ELISA Kit (2)Nectin-2 ELISA Kits are quality controlled by 8 internation QC standards which guarantee every ELISA Kit with high quality.
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Nectin-2 Lysate (6)Nectin-2 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of Nectin-2 protein from the overexpression lysate was verified.
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Nectin-2 cDNA Clone (39)Nectin-2 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Nectin-2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
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Nectin-2 qPCR Primer (3)Verified forward and reverse primers for analyzing the quantitative expression of gene. The primer mix has been verified to generate satisfactory qPCR data on Roche LightCycler480.
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Nectin-2 IP Kit (2)The Anti-Nectin-2 magnetic Beads, conjugated with Anti-Nectin-2 antibody, are used for immuneprecipitation (IP) of Nectin-2 proteins which expressed in vitro expression systems.
Nectin-2 Protein (6)
Nectin-2 Antibody (12)
Nectin-2 ELISA 试剂盒（即用型）& ELISA 抗体对套装（非即用型）(2)
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线性范围: 15.625 pg/ml
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灵敏度: 7.95 pg/mL
Nectin-2 cDNA Clone (39)
NM_001042724.1
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
NM_008990.3
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
NM_001012064.1
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
Nectin-2 qPCR Primer (3)
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Nectin-2 qPCR Primer Pairs, Human HP100092
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Nectin-2 qPCR Primer Pairs, Mouse MP200341
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Nectin-2 qPCR Primer Pairs, Rat RP300298
Nectin-2 IP Kit (2)
Nectin-2 Lysate (6)
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Nectin-2 分子背景
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
Nectin-2 参考文献
- Bachelet I, et al. (2006) Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process. J Biol Chem. 281(37): 27190-6.
- Wang L, et al. (2009) Molecular cloning, characterization and three-dimensional modeling of porcine nectin-2/CD112. Vet Immunol Immunopathol. 132(2-4): 257-63.
