All CD16 reagents are produced in house and quality controlled, including 27 CD16 Antibody, 1 CD16 ELISA, 26 CD16 Gene, 5 CD16 Lysate, 5 CD16 Protein, 1 CD16 qPCR. All CD16 reagents are ready to use.
Recombinant CD16 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-AVI & His.
CD16antibodies are validated with different applications, which are FCM, ELISA(Cap), ELISA, IHC-P, WB, IP, ELISA(Det).
CD16cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD16 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD16ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Expression host: HEK293 Cells
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.