CD25 (Protein|Antibody|cDNA Clone|ELISA Kit)

All CD25 reagents are produced in house and quality controlled, including 31 CD25 Antibody, 52 CD25 Gene, 7 CD25 Lysate, 7 CD25 Protein, 3 CD25 qPCR. All CD25 reagents are ready to use.

Recombinant CD25 proteins are expressed by HEK293 Cells, Baculovirus-Insect Cells with fusion tags as C-His, C-human IgG1-Fc, C-cleavage.

CD25antibodies are validated with different applications, which are ELISA, FCM, IHC-P.

CD25cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD25 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

CD25 Protein (7)

Species

CD25 Protein, Human, Recombinant (His Tag)

10165-H08H

Expression host: HEK293 Cells

Human IL2RA/IL-2RA/CD25 Protein 8474

CD25 Protein, Cynomolgus, Recombinant (His Tag)

90265-C08H

Expression host: HEK293 Cells

Cynomolgus IL2RA/IL-2RA/CD25 Protein 12917

CD25 Protein, Mouse, Recombinant (His Tag)

50292-M08H

Expression host: HEK293 Cells

Mouse IL2RA/IL-2RA/CD25 Protein 11547

CD25 Protein, Human, Recombinant (Fc Tag)

10165-H02H

Expression host: HEK293 Cells

Human IL2RA/IL-2RA/CD25 Protein 8473

CD25 Protein, Cynomolgus, Recombinant (Fc Tag)

90265-C02H

Expression host: HEK293 Cells

Cynomolgus IL2RA/IL-2RA/CD25 Protein 12916

CD25 Protein, Rat, Recombinant (His Tag)

80074-R08B

Expression host: Baculovirus-Insect Cells

Rat IL2RA/IL-2RA/CD25 Protein 18639

CD25 Protein, Cynomolgus, Recombinant

90265-CCCH

Expression host: HEK293 Cells

Cynomolgus IL2RA/IL-2RA/CD25 Protein 12918
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CD25 Antibody (31)

Application Clonality
Host

Anti-CD25 Antibody (PerCP)

10165-MM17-C

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 18888

Anti-CD25 Antibody (PE)

10165-MM17-P

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 15950

Anti-CD25 Antibody

10165-R702

Application: ELISA

Clonality: MAb

Anti-CD25 Antibody (PerCP)

50292-R049-C

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4935

Anti-CD25 Antibody

50292-RP02

Application: ELISA

Clonality: PAb

Anti-CD25 Antibody (PerCP)

10165-R216-C

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 17097

Anti-CD25 Antibody

10165-R216

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4980

Anti-CD25 Antibody

10165-T16

Application: ELISA

Clonality: PAb

Anti-CD25 Antibody

10165-MM14

Application: ELISA

Clonality: MAb

Anti-CD25 Antibody

50292-R049

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4982

Anti-CD25 Antibody

50292-R051

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4983

Anti-CD25 Antibody (PerCP)

50292-R051-C

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4936

Anti-CD25 Antibody

50292-T16

Application: ELISA

Clonality: PAb

Anti-CD25 Antibody (APC)

10165-R216-A

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4981

Anti-CD25 Antibody (PE)

10165-R216-P

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4981

Anti-CD25 Antibody (APC)

10165-MM17-A

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 18491

Anti-CD25 Antibody

10165-RP01

Application: ELISA

Clonality: PAb

Anti-CD25 Antibody

10165-RP02

Application: ELISA

Clonality: PAb

Anti-CD25 Antibody

10165-T24

Application: ELISA,IHC-P

Clonality: PAb

Human IL2RA/IL-2RA/CD25 Immunohistochemistry(IHC) 18268

Anti-CD25 Antibody (APC)

50292-R051-A

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4936

Anti-CD25 Antibody (APC)

50292-R049-A

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4935

Anti-CD25 Antibody (FITC)

50292-R051-F

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4936

Anti-CD25 Antibody (FITC)

10165-R216-F

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4981

Anti-CD25 Antibody (FITC)

10165-MM17-F

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 15947

Anti-CD25 Antibody (FITC)

50292-R049-F

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4935

Anti-CD25 Antibody (PE)

50292-R051-P

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4936

Anti-CD25 Antibody

10165-MM17

Application: FCM

Clonality: MAb

Human IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 15958

Anti-CD25 Antibody

50292-R186

Application: ELISA

Clonality: MAb

Anti-CD25 Antibody

50292-RP01

Application: ELISA

Clonality: PAb

Anti-CD25 Antibody (PE)

50292-R049-P

Application: FCM

Clonality: MAb

Mouse IL2RA/IL-2RA/CD25 Flow Cytometry (FC) 4935

Anti-CD25 Antibody

90265-RP01

Application: ELISA

Clonality: PAb

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CD25 cDNA Clone (52)

Mouse
Rhesus
Human
Rat

CD25 qPCR Primer (3)

CD25 Lysate (7)

CD25 (alpha-chain of IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling. The IL2RA (CD25) gene is a substantial component of the high-affinity receptor molecule highly expressed by activated T lymphocytes. Recently, a strong evidence was obtained for the involvement of IL-2RA in conferring susceptibility to type 1 diabetes (T1D). Cancer growth and development is associated with the stimulation of the innate immune system, including enhanced interleukin 2 receptor (IL-2R) expression in immune cells and its shedding into the circulation in a soluble form of sIL-2Ralpha. In most haematological malignancies, including different types of leukaemias and lymphomas, sIL-2Ralpha has been found to be released directly from the surface of neoplastic cells thus reflecting the tumour bulk, turnover and activity. Several studies have proved that not only lymphoid cancer cells, but also some non-lymphoid cancer cells, express IL-2R on their surface. They include malignant melanoma and carcinomas of the kidney, head and neck, oesophagus and lung. Thus, sIL-2Ralpha is elevated in most proliferative disturbances of the hematopoietic system and in many solid tumors.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

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