CD38 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All CD38 reagents are produced in house and quality controlled, including 26 CD38 Antibody, 2 CD38 ELISA, 65 CD38 Gene, 3 CD38 IP Kit, 9 CD38 Lysate, 10 CD38 Protein, 3 CD38 qPCR. All CD38 reagents are ready to use.

CD38 Protein (10)

CD38 Antibody (26)

CD38 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

CD38 cDNA Clone (65)

NM_001775.2

克隆载体 cDNA 产品

In lentiviral vector

NM_007646.4

克隆载体 cDNA 产品

In lentiviral vector

NM_013127.1

克隆载体 cDNA 产品

In lentiviral vector

XM_005554514.1

克隆载体 cDNA 产品

In lentiviral vector

NM_001082683.1

克隆载体 cDNA 产品

In lentiviral vector

CD38 Lysate (9)

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CD38 分子背景

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

CD38 参考文献

  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.