All CD40 reagents are produced in house and quality controlled, including 27 CD40 Antibody, 2 CD40 ELISA, 41 CD40 Gene, 1 CD40 IPKit, 11 CD40 Lysate, 14 CD40 Protein, 3 CD40 qPCR. All CD40 reagents are ready to use.
Recombinant CD40 proteins are expressed by HEK293 Cells, Yeast with fusion tags as C-His, C-human IgG1-Fc, C-human IgG1-Fc & His, C-rabbit IgG-Fc, C-cleavage.
CD40antibodies are validated with different applications, which are FCM, ELISA, ELISA(Det), WB, ELISA(Cap), IHC-P, ICC/IF, IF, IP.
CD40cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD40 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD40ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
Immune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: ICC Antibodies Immune Checkpoint Detection: IP Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets