CD52 cDNA ORF Clone in Cloning Vector, Rat

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CD52 cDNA ORF Clone in Cloning Vector, Rat: 产品信息

基因
种属
Rat
NCBI 参考序列号
基因长度
291 bp
序列特征
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 65 A/T resulting in the amino acid Asp substitution by Val and 54 C/A not causing the amino acid variation.
产品特征
Full length Clone DNA of Rat CD52 antigen.
质粒
载体
测序引物
SP6 and T7 or M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

CD52 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CD52 背景信息

CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
全称
CD52 molecule
参考文献
  • Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.
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