Fas Ligand cDNA ORF Clone in Cloning Vector, Mouse

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Fas Ligand cDNA ORF Clone in Cloning Vector, Mouse: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
840 bp
序列特征
Identical with the Gene Bank Ref. ID sequence except for three point mutations: 550 A/G resulting in the amino acid Thr substitution by Ala, 653 A/G resulting in the amino acid Glu substitution by Gly, 567 G/A not causing the amino acid variation.
产品特征
Full length Clone DNA of Mouse Fas ligand (TNF superfamily, member 6).
质粒
载体
测序引物
SP6 and T7 or M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Fas Ligand cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Fas Ligand cDNA ORF Clone in Cloning Vector, Mouse: 别称

Apt1lg1 cDNA ORF Clone, Mouse; CD178 cDNA ORF Clone, Mouse; CD95-L cDNA ORF Clone, Mouse; Cd95l cDNA ORF Clone, Mouse; Fas-L cDNA ORF Clone, Mouse; Fasl cDNA ORF Clone, Mouse; Faslg cDNA ORF Clone, Mouse; gld cDNA ORF Clone, Mouse; Tnfsf6 cDNA ORF Clone, Mouse

Fas Ligand 背景信息

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
全称
Fas ligand
参考文献
  • Pitti R M. et al., 1998, Nature. 396 (6712): 699-703.
  • Hane M. et al., 1995, FEBS Lett. 373 (3): 265-8.
  • Schneider P. et al., 1997, J Biol Chem. 272 (30): 18827-33.

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