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CDK16/PCTK1/PCTAIRE1  蛋白,抗体,试剂盒,cDNA克隆

CDK16/PCTK1/PCTAIRE1 相关信号通路

CDK16/PCTK1/PCTAIRE1 概述&蛋白信息

CDK16/PCTK1/PCTAIRE1 研究背景

基因概述: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
General information above from NCBI
催化活性: ATP + a protein = ADP + a phosphoprotein.
亚单位结构: Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Interacts with NSF. Identified in a complex with NSF, syntaxin-1, synaptotagmin, SYN1, SYP and CDK5R1 (By similarity). Interacts with BRSK2. Interacts with CCNY; this increases the CDK16 kinase activity.
亚细胞定位: Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome (By similarity). Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
组织特异性: Detected in pancreas islets (at protein level). Detected in brain and pancreas.
翻译后修饰: Phosphorylation at Ser-153 inhibits kinase activity.
相似的序列: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Contains 1 protein kinase domain.
General information above from UniProt

CDK16/PCTK1/PCTAIRE1 别称

CDK16/PCTK1/PCTAIRE1 相关文献

请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”