快速订购

CDKL2  蛋白,抗体,试剂盒,cDNA克隆

CDKL2 相关研究领域

CDKL2 相关信号通路

    CDKL2 概述&蛋白信息

    CDKL2 研究背景

    基因概述: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.
    General information above from NCBI
    催化活性: ATP + a protein = ADP + a phosphoprotein.
    结构域: The [NKR]KIAxRE motif seems to be a cyclin-binding region.
    亚细胞定位: Cytoplasm {ECO:0000269|PubMed:9000130}. Nucleus {ECO:0000269|PubMed:9000130}.
    组织特异性: Expressed in testis and kidney, and at lower level in brain and lung. {ECO:0000269|PubMed:9000130}.
    相似的序列: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. {ECO:0000305}.; Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
    General information above from UniProt

    Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus, amygdala, and dorsal thalamus. The high expression in these brain regions suggests that Cdkl2 may have functions in congnition and emotion processes. Cdkl2 accumulates primarily in the cytoplasm, with lower levels in the nucleus.

    CDKL2 别称

    P56,KKIAMRE, [homo-sapiens]
    CDKL2,KKIAMRE,P56, [human]
    5330436L21Rik,AI505225,KKIAMRE,Kkm,MGC144031,MGC144032,Cdkl2, [mouse]
    Kkm,KKIAMRE,AI505225,5330436L21Rik, [mus-musculus]

    CDKL2 相关文献

  • Sassa T, et al. (2003) Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus. Cell and Tissue Research. 315 (2): 147-56.
  • Rosenblatt J, et al. (1992) Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. PNAS. 89 (7): 2824-8.
  • Mironov V, et al. (1999) Cyclin-Dependent Kinases and Cell Division in Plants-The Nexus. The Plant Cell. 11 (4): 509-22.
  • 请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”