CEACAM6 Matched ELISA Antibody Pair Set,Human

1/1
Price:
Size:
Number:

CEACAM6 Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
CEACAM6 Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human CEACAM6
线性范围
15.6-1000 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 1 mg/mL of mouse anti-CEACAM6 monoclonal antibody. Dilute to a working concentration of 2 μg/mL in PBS before coating.
2. Detection Antibody 0.4 mg/mL of biotinylated rabbit anti-CEACAM6 polyclonal antibody. Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use.
3. Standard Each vial contains 88 ng of recombinant CEACAM6. Reconstitute standard powder with 1 mL detection antibody dilution buffer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 1000 pg/mL is recommended.
4. Streptavidin-HRP 50 μL of streptavidin conjugated to horseradish-peroxidase. 1:2000 Dilution in detection antibody dilution buffer before use.
产品概述
This CEACAM6 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human CEACAM6 . It contains Human CEACAM6 capture antibody, Human CEACAM6 detector antibody (Biotin) Streptavidin-HRP and a highly purified HEK293-expressed recombinant Human CEACAM6 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
Streptavidin-HRP: Store at 4℃ and protect it from prolonged exposure to light. DO NOT FREEZE! It is stable for up to 6 months from date of receipt.

CEACAM6 Matched ELISA Antibody Pair Set,Human 图片

CEACAM6 Matched ELISA Antibody Pair Set,Human: 别称

CD66c Matched ELISA Antibody Pair Set, Human; CEA Matched ELISA Antibody Pair Set, Human; CEAL Matched ELISA Antibody Pair Set, Human; NCA Matched ELISA Antibody Pair Set, Human

CEACAM6 背景信息

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
全称
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
参考文献
  • Duxbury MS, et al. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 23(34): 5834-42.
  • Lewis-Wambi JS, et al. (2008) Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells. Eur J Cancer. 44(12): 1770-9.
  • Influences of enteral nutrition upon CEACAM6 expression by intestinal epithelial cells
    Author
    Keenan, JI;Hooper, EM;Tyrer, PC;Day, AS;
    Year
    2013
    Journal
    Innate Immun
    Application
    ELISA
  • The Role of Biliary Carcinoembryonic Antigen-Related Cellular Adhesion Molecule 6 (CEACAM6) as a Biomarker in Cholangiocarcinoma
    Author
    Rose, JB;Correa-Gallego, C;Li, Y;Nelson, J;Alseidi, A;Helton, WS;Allen, PJ;D'Angelica, MI;DeMatteo, RP;Fong, Y;Kingham, TP;Kowdley, KV;Jarnagin, WR;Rocha, FG;
    Year
    2016
    Journal
    PLoS ONE
    Application
    ELISA
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后