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CLEC4B2 / mDCAR1 抗体, 兔多抗, 抗原亲和纯化

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大鼠 CLEC4B2 抗体产品信息
免疫原:Recombinant Rat CLEC4B2 / mDCAR1 protein (Catalog#80265-R07H)
克隆号:
Ig 类型:Rabbit IgG
浓度:
内毒素:
缓冲液:0.2 μm filtered solution in PBS
抗体制备方法:Produced in rabbits immunized with purified, recombinant Rat CLEC4B2 / mDCAR1 (rh CLEC4B2 / mDCAR1; Catalog#80265-R07H; Q67DU9; Met44-Leu208). CLEC4B2 / mDCAR1 specific IgG was purified by Rat CLEC4B2 / mDCAR1 affinity chromatography.
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CLEC4B2 / mDCAR1 研究背景

Clec4b2, also known as mDCAR1, is a member of the DCIR/DCAR family. Expression of Clec4b2 was strongly tissue dependent. Clec4b2 expression on DCs was restricted to the CD8(+) DC subset in spleen and thymus and on subpopulations of CD11b(+) myeloid cells in bone marrow and spleen, whereas the molecule was not detectable on both cell types in lymph nodes and peripheral blood. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune responses by CLRs.

大鼠 CLEC4B2 / mDCAR1 参考资料
  • Katayama S. et al., 2005, Science. 309 (5740): 1564-6.
  • Kaden SA. et al., 2009, J Immunol. 183 (8): 5069-78.
  • Skarnes WC. et al., 2011, Nature. 474 (7351): 337-42.
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    货号: 80265-T16-200
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