CXCL5 cDNA ORF Clone, Mouse, C-His tag

Cat: MG50354-M-H
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CXCL5 cDNA ORF Clone, Mouse, C-His tag 基本信息
基因
种属
Mouse
NCBI 参考序列号
参考序列ORF长度
399 bp
序列描述
Identical with the Gene Bank Ref.ID sequence.
描述
Full length Clone DNA of Mouse chemokine (C-X-C motif) ligand 5 with His tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV/hygro-His
限制性酶切位点
KpnI + XhoI (5.5kb + 0.43kb)
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Ampicillin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
CXCL5 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CXCL5 cDNA ORF Clone, Mouse, C-His tag Validated Images
Mouse CXCL5 Gene Plasmid Map 7579
CXCL5 cDNA ORF Clone, Mouse, C-His tag Alternative Names
AMCF-II cDNA ORF Clone, Mouse;ENA-78 cDNA ORF Clone, Mouse;GCP-2 cDNA ORF Clone, Mouse;LIX cDNA ORF Clone, Mouse;Scyb5 cDNA ORF Clone, Mouse;Scyb6 cDNA ORF Clone, Mouse
CXCL5 Background Information

CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.

Full Name
chemokine (C-X-C motif) ligand 5
References
  • Dawes JM, et al. (2011) CXCL5 Mediates UVB Irradiation-Induced Pain. Sci Transl Med. 3(90): 90ra60.
  • O'Donovan N, et al. (1999) Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84(1-2):39-42.
  • Persson T, et al. (2003) Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils. Clin Exp Allergy. 33(4):531-7.
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