RBP4 cDNA ORF Clone, Canine, C-DDK (Flag®) tag

Cat: DG70006-CF

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RBP4 cDNA ORF Clone, Canine, C-DDK (Flag®) tag 基本信息

基因

种属
Canine
NCBI 参考序列号
参考序列ORF长度
606 bp
描述
Full length Clone DNA of Canine retinol binding protein 4, plasma with C terminal Flag tag.

质粒

启动子
Enhanced CMV promoter
载体
标签序列
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

RBP4 Background Information

Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM).

Full Name
retinol binding protein 4, plasma
References
  • Yang Q, et al. (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 436(7049): 356-62.
  • Choi SH, et al. (2008) High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus. J Clin Endocrinol Metab. 93(8): 3142-8.
  • Tepper BJ, et al. (2010) Serum retinol-binding protein 4 (RBP4) and retinol in a cohort of borderline obese women with and without gestational diabetes. Clin Biochem. 43(3): 320-3.
  • RBP4 cDNA ORF Clone, Canine, Related Products

    Product Name Catalog#(PDF)
    RBP4 cDNA ORF Clone in Cloning Vector, Canine DG70006-G
    RBP4 cDNA ORF Clone, Canine, untagged DG70006-UT
    RBP4 Lentiviral cDNA ORF Clone, Canine, C-GFPSpark® tag DG70006-ACGLN
    RBP4 cDNA ORF Clone, Canine, C-GFPSpark® tag DG70006-ACG
    RBP4 cDNA ORF Clone, Canine, C-OFPSpark® tag DG70006-ACR
    RBP4 cDNA ORF Clone, Canine, N-DDK (Flag®) tag DG70006-NF
    RBP4 cDNA ORF Clone, Canine, C-His tag DG70006-CH
    RBP4 cDNA ORF Clone, Canine, N-His tag DG70006-NH
    RBP4 cDNA ORF Clone, Canine, C-HA tag DG70006-CY
    RBP4 cDNA ORF Clone, Canine, N-HA tag DG70006-NY
    RBP4 cDNA ORF Clone, Canine, C-Myc tag DG70006-CM
    RBP4 cDNA ORF Clone, Canine, N-Myc tag DG70006-NM

    RBP4 cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
    RBP4 cDNA ORF Clone in Cloning Vector, Rat RG80008-G
    RBP4 cDNA ORF Clone, Rat, untagged RG80008-UT
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    RBP4 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80008-ACGLN
    RBP4 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80008-ACR
    RBP4 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80008-CF
    RBP4 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80008-NF
    RBP4 cDNA ORF Clone, Rat, C-His tag RG80008-CH
    RBP4 cDNA ORF Clone, Rat, N-His tag RG80008-NH
    RBP4 cDNA ORF Clone, Rat, C-HA tag RG80008-CY
    RBP4 cDNA ORF Clone, Rat, N-HA tag RG80008-NY
    RBP4 cDNA ORF Clone, Rat, C-Myc tag RG80008-CM
    RBP4 cDNA ORF Clone, Rat, N-Myc tag RG80008-NM
    RBP4 qPCR Primer Pairs, Rat RP300007

    RBP4 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    RBP4 cDNA ORF Clone in Cloning Vector, Mouse MG50170-M
    RBP4 cDNA ORF Clone, Mouse, untagged MG50170-UT
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    RBP4 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50170-ACG
    RBP4 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50170-ACR
    RBP4 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50170-CF
    RBP4 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50170-NF
    RBP4 cDNA ORF Clone, Mouse, C-His tag MG50170-CH
    RBP4 cDNA ORF Clone, Mouse, N-His tag MG50170-NH
    RBP4 cDNA ORF Clone, Mouse, C-HA tag MG50170-CY
    RBP4 cDNA ORF Clone, Mouse, N-HA tag MG50170-NY
    RBP4 cDNA ORF Clone, Mouse, C-Myc tag MG50170-CM
    RBP4 cDNA ORF Clone, Mouse, N-Myc tag MG50170-NM
    RBP4 qPCR Primer Pairs, Mouse MP200200

    RBP4 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    RBP4 cDNA ORF Clone in Cloning Vector, Human HG10354-M
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    RBP4 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10354-ACGLN
    RBP4 cDNA ORF Clone, Human, C-GFPSpark® tag HG10354-ACG
    RBP4 cDNA ORF Clone, Human, C-OFPSpark® tag HG10354-ACR
    RBP4 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10354-CF
    RBP4 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10354-NF
    RBP4 cDNA ORF Clone, Human, C-His tag HG10354-CH
    RBP4 cDNA ORF Clone, Human, N-His tag HG10354-NH
    RBP4 cDNA ORF Clone, Human, C-HA tag HG10354-CY
    RBP4 cDNA ORF Clone, Human, N-HA tag HG10354-NY
    RBP4 cDNA ORF Clone, Human, C-Myc tag HG10354-CM
    RBP4 cDNA ORF Clone, Human, N-Myc tag HG10354-NM
    RBP4 qPCR Primer Pairs, Human HP100080
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