All C7 reagents are produced in house and quality controlled, including 4 C7 Antibody, 1 C7 ELISA, 15 C7 Gene, 2 C7 Lysate, 2 C7 Protein, 1 C7 qPCR. All C7 reagents are ready to use.
Recombinant C7 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.
C7antibodies are validated with different applications, which are ELISA(Cap), ELISA.
C7cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each C7 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
C7ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Complement component 7 is a component of the complement system. It belongs to the complement C6/C7/C8/C9 family. It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and 2 TSP type-1 domains. Complement component 7 serves as a membrane anchor. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. It is a constituent of MAC that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.