DDR2 (Protein|Antibody|cDNA Clone|ELISA Kit)

All DDR2 reagents are produced in house and quality controlled, including 5 DDR2 Antibody, 52 DDR2 Gene, 8 DDR2 Lysate, 8 DDR2 Protein, 3 DDR2 qPCR. All DDR2 reagents are ready to use.

Recombinant DDR2 proteins are expressed by HEK293 Cells, Baculovirus-Insect Cells with fusion tags as C-human IgG1-Fc, C-His, N-GST & His, C-cleavage.

DDR2antibodies are validated with different applications, which are ELISA, IHC-P.

DDR2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each DDR2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

DDR2 Protein (8)

Species

DDR2 Protein, Rhesus, Recombinant (Fc Tag)

90228-C02H

Expression host: HEK293 Cells

Rhesus DDR2/CD167b Protein 12898

DDR2 Protein, Rat, Recombinant (Fc Tag)

80341-R02H

Expression host: HEK293 Cells

Rat DDR2/CD167b Protein 12577

DDR2 Protein, Rat, Recombinant (His Tag)

80341-R08H

Expression host: HEK293 Cells

Rat DDR2/CD167b Protein 12578

DDR2 Protein, Rhesus, Recombinant (His Tag)

90228-C08H

Expression host: HEK293 Cells

Rhesus DDR2/CD167b Protein 12899

DDR2 Protein, Human, Recombinant (aa 422-855, His & GST Tag)

10209-H20B1

Expression host: Baculovirus-Insect Cells

Human DDR2/CD167b Protein 8548

DDR2 Protein, Human, Recombinant (Fc Tag)

10209-H02H

Expression host: HEK293 Cells

Human DDR2/CD167b Protein 8546

DDR2 Protein, Mouse, Recombinant (His Tag)

50541-M08H

Expression host: HEK293 Cells

Mouse DDR2/CD167b Protein 11714

DDR2 Protein, Human, Recombinant (His Tag)

10209-H08H

Expression host: HEK293 Cells

Human DDR2/CD167b Protein 8547
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DDR2 Antibody (5)

Application Clonality
Host

Anti-DDR2 Antibody

10209-T16

Application: ELISA

Clonality: PAb

Anti-DDR2 Antibody

50541-RP02

Application: ELISA,IHC-P

Clonality: PAb

Mouse DDR2/CD167b Immunohistochemistry(IHC) 3315

Anti-DDR2 Antibody

90228-T16

Application: ELISA

Clonality: PAb

Anti-DDR2 Antibody

50541-RP01

Application: ELISA

Clonality: PAb

Anti-DDR2 Antibody

50541-R102

Application: ELISA

Clonality: MAb

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DDR2 cDNA Clone (52)

Mouse
Rhesus
Human
Rat

DDR2 qPCR Primer (3)

DDR2 Lysate (8)

Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2, up-regulates matrix metallloproteinase 1 (MMP-1) and MMP-2 expression in cellular matrix. DDR2/CD167b was found to recognise the triple-helical region of collagen X as well as the NC1 domain. Binding to the collagenous region was dependent on the triple-helical conformation. DDR2/CD167b autophosphorylation was induced by the collagen X triple-helical region but not the NC1 domain, indicating that the triple-helical region of collagen X contains a specific DDR2 binding site that is capable of receptor activation. DDR2/CD167b is induced during stellate cell activation and implicate the phosphorylated receptor as a mediator of MMP-2 release and growth stimulation in response to type I collagen. Moreover, type I collagen-dependent upregulation of DDR2/CD167b expression establishes a positive feedback loop in activated stellate cells, leading to further proliferation and enhanced invasive activity.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

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Antibody
Gene
qPCR
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