Anti-EFNB2A Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Danio rerio (zebrafish)
Danio rerio (zebrafish) EFNB2A
Recombinant Danio rerio (zebrafish) EFNB2A / Ephrin B2a protein (Catalog#63002-Z08H)
Produced in rabbits immunized with purified, recombinant Danio rerio (zebrafish) EFNB2A / Ephrin B2a (Catalog#63002-Z08H; O73874; Met 1-Ala222). EFNB2A / Ephrin B2a specific IgG was purified by Danio rerio (zebrafish) EFNB2A / Ephrin B2a affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-EFNB2A Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-EFNB2A Antibody Alternative Names
Anti-efnb2 Antibody;Anti-EFNB2A Antibody
EFNB2A Background Information
Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.
Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60. Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26. Patten SA. et al., 2012, PLoS One. 7 (2): e31650.