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小鼠 EphA3 蛋白 (aa 569-984)

  • Mouse EphA3 Protein (aa 569-984) SDS-PAGE
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小鼠 EPHA3 蛋白产品信息
分子别称:AW492086,Cek4,End3,ETK1,Hek,Hek4,Mek4,Tyro4
蛋白构建:A DNA sequence encoding the mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with two additional amino acids (Gly & Pro ) at the N-terminus.
分子种属:Mouse
表达宿主:Baculovirus-Insect cells
运输说明:Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
Shipment made at ambient temperature may seriously affect the activity of the ordered products.
小鼠 EPHA3 蛋白质控检测
纯度:> 85 % as determined by SDS-PAGE
生物活性:Kinase activity untested
内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
稳定性:Samples are stable for up to twelve months from date of receipt at -70℃
预测N端:Gly
分子量:The recombinant mouse EPHA3 consists of 418 amino acids and has a calculated molecular mass of 46.6 kDa. The recombinant protein migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions.
缓冲液:Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
小鼠 EPHA3 蛋白使用指导
储存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶条件:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
小鼠 EPHA3 蛋白SDS-PAGE
Mouse EphA3 Protein (aa 569-984) SDS-PAGE

EPHA3 相关信号通路

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EPHA3/Eph Receptor A3 研究背景

EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

小鼠 EPHA3/Eph Receptor A3 参考资料
  • Holder N, et al. (1999) Eph receptors and ephrins: effectors of morphogenesis. Development. 126(10):2033-44.
  • Wilkinson DG. (2000) Eph receptors and ephrins: regulators of guidance and assembly. Int Rev Cytol. 196:177-244.
  • Xu Q, et al. (2001) Roles of Eph receptors and ephrins in segmental patterning. Philos Trans R Soc Lond B Biol Sci. 355(1399):993-1002.
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    货号: 51122-MNCB-20
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    Datasheet & Documentation

    产品数据可能随批次变化,最新数据请详见随货说明书。
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”