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小鼠 Ephrin B3 / EFNB3 蛋白 (ECD, Fc 标签)

  • Efnb3 protein SDS-PAGE
产品数据评论相关产品实验方法
小鼠 Efnb3 蛋白产品信息
分子别称:EFL-6,ELF-3,Elk-L3,Epl8,LERK-8,NLERK-2
蛋白构建:A DNA sequence encoding the mouse Efnb3 (NP_031937.1) (Met1-Ala227) was expressed with the Fc region of human IgG1 at the C-terminus.
分子种属:Mouse
表达宿主:Human Cells
运输说明:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
小鼠 Efnb3 蛋白质控检测
纯度:> 95 % as determined by SDS-PAGE.
生物活性:1.Measured by its binding ability in a functional ELISA.
2.Immobilized mouse EPHB3-His(Cat:50581-M08H) at 10μg/mL (100μL/well) can bind mouse EFNB3-Fc(Cat:51147-M02H), the EC50 of mouse EFNB3-Fc is 1-50 ng/mL.
内毒素:<1.0 EU per μg protein as determined by the LAL method.
稳定性:Samples are stable for up to twelve months from date of receipt at -70℃
预测N端:Leu 28
分子量:The recombinant mouse Efnb3 consists 438 amino acids and predicts a molecular mass of 48.8 kDa.
缓冲液:Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
小鼠 Efnb3 蛋白使用指导
储存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶条件:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
小鼠 Efnb3 蛋白SDS-PAGE
Efnb3 protein SDS-PAGE

Efnb3 相关信号通路

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    Ephrin B3 / EFNB3 研究背景

    Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions. Ephrin B3 binds to, and induce the collapse of, commissural axons/growth cones in vitro. It may play a role in constraining the orientation of longitudinally projecting axons.

    小鼠 Ephrin B3 / EFNB3 参考资料
  • Takemoto M, et al. (2002) Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro. Eur J Neurosci. 16(6):1168-72.
  • Brckner K, et al. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 22(3):511-24.
  • Bergemann A, et al. (1998) Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16(4):471-80.
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    货号: 51147-M02H-100
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    Datasheet & Documentation

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    产品数据可能随批次变化,最新数据请详见随货说明书。
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”