CD8 alpha cDNA ORF Clone, Ferret, N-Myc tag

Cat: FG60001-NM

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CD8 alpha cDNA ORF Clone, Ferret, N-Myc tag 基本信息

基因

种属
Ferret
NCBI 参考序列号
参考序列ORF长度
739 bp
描述
Full length Clone DNA of Ferret CD8 antigen with N terminal Myc tag.

质粒

启动子
Enhanced CMV promoter
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CD8 alpha Background Information

T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I  membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

Full Name
CD8a molecule
References
References Devine, L. et al., 2000, J Immunol. 164 (2): 833-8. Arcaro, A. et al., 2000, J Immunol. 165 (4): 2068-76. Saha, K. et al., 2001, Nat Med. 7 (1): 65-72. Romero, P. et al., 2005, Eur J Immunol. 35 (11): 3092-4.

CD8 alpha cDNA ORF Clone, Ferret, Related Products

Product Name Catalog#(PDF)
CD8 alpha cDNA ORF Clone in Cloning Vector, Ferret FG60001-G
CD8 alpha cDNA ORF Clone, Ferret, untagged FG60001-UT
CD8 alpha cDNA ORF Clone, Ferret, C-GFPSpark® tag FG60001-ACG
CD8 alpha Lentiviral cDNA ORF Clone, Ferret, C-GFPSpark® tag FG60001-ACGLN
CD8 alpha cDNA ORF Clone, Ferret, C-OFPSpark® tag FG60001-ACR
CD8 alpha cDNA ORF Clone, Ferret, C-DDK (Flag®) tag FG60001-CF
CD8 alpha cDNA ORF Clone, Ferret, N-DDK (Flag®) tag FG60001-NF
CD8 alpha cDNA ORF Clone, Ferret, C-His tag FG60001-CH
CD8 alpha cDNA ORF Clone, Ferret, N-His tag FG60001-NH
CD8 alpha cDNA ORF Clone, Ferret, C-HA tag FG60001-CY
CD8 alpha cDNA ORF Clone, Ferret, N-HA tag FG60001-NY
CD8 alpha cDNA ORF Clone, Ferret, C-Myc tag FG60001-CM

CD8 alpha cDNA ORF Clone, Cynomolgus, Related Products

Product Name Catalog#(PDF)
CD8 alpha cDNA ORF Clone, Cynomolgus, untagged CG90888-UT

CD8 alpha cDNA ORF Clone, Rat, Related Products

Product Name Catalog#(PDF)
CD8 alpha cDNA ORF Clone in Cloning Vector, Rat RG80285-G
CD8 alpha cDNA ORF Clone, Rat, untagged RG80285-UT
CD8 alpha cDNA ORF Clone, Rat, C-GFPSpark® tag RG80285-ACG
CD8 alpha Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80285-ACGLN
CD8 alpha cDNA ORF Clone, Rat, C-OFPSpark® tag RG80285-ACR
CD8 alpha cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80285-CF
CD8 alpha cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80285-NF
CD8 alpha cDNA ORF Clone, Rat, C-His tag RG80285-CH
CD8 alpha cDNA ORF Clone, Rat, N-His tag RG80285-NH
CD8 alpha cDNA ORF Clone, Rat, C-HA tag RG80285-CY
CD8 alpha cDNA ORF Clone, Rat, N-HA tag RG80285-NY
CD8 alpha cDNA ORF Clone, Rat, C-Myc tag RG80285-CM
CD8 alpha cDNA ORF Clone, Rat, N-Myc tag RG80285-NM
CD8 alpha qPCR Primer Pairs, Rat RP300390

CD8 alpha cDNA ORF Clone, Mouse, Related Products

Product Name Catalog#(PDF)
CD8 alpha cDNA ORF Clone in Cloning Vector, Mouse MG50389-M
CD8 alpha cDNA ORF Clone, Mouse, untagged MG50389-UT
CD8 alpha Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50389-ACGLN
CD8 alpha cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50389-ACG
CD8 alpha cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50389-ACR
CD8 alpha cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50389-CF
CD8 alpha cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50389-NF
CD8 alpha cDNA ORF Clone, Mouse, C-His tag MG50389-CH
CD8 alpha cDNA ORF Clone, Mouse, N-His tag MG50389-NH
CD8 alpha cDNA ORF Clone, Mouse, C-HA tag MG50389-CY
CD8 alpha cDNA ORF Clone, Mouse, N-HA tag MG50389-NY
CD8 alpha cDNA ORF Clone, Mouse, C-Myc tag MG50389-CM
CD8 alpha cDNA ORF Clone, Mouse, N-Myc tag MG50389-NM
CD8 alpha qPCR Primer Pairs, Mouse MP200408

CD8 alpha cDNA ORF Clone, Human, Related Products

Product Name Catalog#(PDF)
CD8 alpha cDNA ORF Clone in Cloning Vector, Human HG10980-M
CD8 alpha cDNA ORF Clone, Human, untagged HG10980-UT
CD8 alpha Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10980-ACGLN
CD8 alpha cDNA ORF Clone, Human, C-GFPSpark® tag HG10980-ACG
CD8 alpha cDNA ORF Clone, Human, C-OFPSpark® tag HG10980-ACR
CD8 alpha cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10980-CF
CD8 alpha cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10980-NF
CD8 alpha cDNA ORF Clone, Human, C-His tag HG10980-CH
CD8 alpha cDNA ORF Clone, Human, N-His tag HG10980-NH
CD8 alpha cDNA ORF Clone, Human, C-HA tag HG10980-CY
CD8 alpha cDNA ORF Clone, Human, N-HA tag HG10980-NY
CD8 alpha cDNA ORF Clone, Human, C-Myc tag HG10980-CM
CD8 alpha cDNA ORF Clone, Human, N-Myc tag HG10980-NM
CD8 alpha qPCR Primer Pairs, Human HP100945
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