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人 IBA1/AIF1 基因ORF全长cDNA克隆(表达载体)

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Human AIF1 cDNA Clone产品信息
NCBI注册码:BC009474
参考序列ORF长度:444bp
cDNA基因描述:Full length Clone DNA of Homo sapiens allograft inflammatory factor 1.
分子别称:DADB-70P7.8, AIF-1, IBA1, IRT-1, IRT1, AIF1
分子种属:Human
载体:pCMV3-untagged
质粒:pCMV3-AIF1
限制性酶切位点:KpnI + XbaI (6.1kb + 0.44kb)
Tag序列:
序列信息:Identical with the Gene Bank Ref. ID sequence.
测序引物:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
启动子:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
抗生素(大肠杆菌):Ampicilin
抗生素(哺乳动物细胞):Hygromycin
运输方式:Each tube contains lyophilized plasmid.
储存方法:The lyophilized plasmid can be stored at room temperature for three months.
Human AIF1 基因质粒图
Human AIF1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
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研究背景

AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.

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货号: HG14227-UT
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  • Human AIF1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
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