CD3G cDNA ORF Clone, Human, C-HA tag

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CD3G cDNA ORF Clone, Human, C-HA tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
549 bp
产品特征
Full length Clone DNA of Human CD3g molecule, gamma (CD3-TCR complex) with C terminal HA tag.
质粒
启动子
Enhanced CMV promoter
载体
标签序列
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

CD3G cDNA ORF Clone, Human, C-HA tag: 别称

CD3-GAMMA cDNA ORF Clone, Human; IMD17 cDNA ORF Clone, Human; T3G cDNA ORF Clone, Human

CD3G 背景信息

CD3G gene encodes CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the TCR alpha/beta and gamma/delta heterodimers, forms the TCR-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The CD3 gamma chain has long been considered to mediate targeting to lysosomes for degradation. Defects in this gene are associated with T cell immunodeficiency. Further, it has been proposed as one of the important candidate genes for cancer development due to its pivotal roles in TCR signaling pathway.
全称
CD3g molecule, gamma (CD3-TCR complex)
参考文献
  • Jiang L, Xu J, Ni J, et al. A Functional Insertion/Deletion Polymorphism in the Proximal Promoter of CD3G Is Associated with Susceptibility for Hepatocellular Carcinoma in Chinese Population. DNA and Cell Biology.
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