CD52 cDNA ORF Clone, Human, N-His tag

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CD52 cDNA ORF Clone, Human, N-His tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
186 bp
产品特征
Full length Clone DNA of Human CD52 molecule with N terminal His tag.
质粒
启动子
Enhanced CMV promoter
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

CD52 cDNA ORF Clone, Human, N-His tag: 别称

CDW52 cDNA ORF Clone, Human

CD52 背景信息

CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
全称
CD52 molecule
参考文献
  • Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.
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