CD68 cDNA ORF Clone, Human, untagged

Cat: HG11192-UT
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All CD68 Reagents
CRO Services
Product recommended

All CD68 Reagents
CD68 cDNA ORF Clone, Human, untagged 基本信息
基因
种属
Human
NCBI 参考序列号
参考序列ORF长度
1065 bp
序列描述
Identical with the Gene Bank Ref. ID sequence.
描述
Full length Clone DNA of Human CD68 molecule, transcript variant 1.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-untagged
限制性酶切位点
KpnI + XbaI (6.1kb + 1.07kb)
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Ampicillin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
CD68 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CD68 cDNA ORF Clone, Human, untagged Validated Images
other Green fluorescent protein / GFP Gene Plasmid Map 5613
CD68 cDNA ORF Clone, Human, untagged Alternative Names
GP110 cDNA ORF Clone, Human;LAMP4 cDNA ORF Clone, Human;SCARD1 cDNA ORF Clone, Human
CD68 Background Information

Macrosialin, also known as CD68 and Gp110, is a single-pass type I  membrane protein which belongs to the LAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Full Name
CD68 molecule
References
  • Strobl H. et al., 1995, Br J Haematol. 90 (4): 774-82.
  • Ogawa Y. et al., 1995, Pathol Int. 45 (9): 698-701.
  • Sadovnikova E. et al., 2002,Leukemia. 16 (10): 2019-26.
  • Gottfried E. et al., 2008, Scand J Immunol. 67 (5): 453-63.
  • Strojnik T. et al., 2009, Anticancer Res. 29 (8): 3269-79.
  • CD68 cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
    CD68 cDNA ORF Clone in Cloning Vector, Rat RG80307-G
    CD68 cDNA ORF Clone, Rat, untagged RG80307-UT
    CD68 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80307-ACGLN
    CD68 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80307-ACG
    CD68 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80307-ACR
    CD68 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80307-CF
    CD68 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80307-NF
    CD68 cDNA ORF Clone, Rat, C-His tag RG80307-CH
    CD68 cDNA ORF Clone, Rat, N-His tag RG80307-NH
    CD68 cDNA ORF Clone, Rat, C-HA tag RG80307-CY
    CD68 cDNA ORF Clone, Rat, N-HA tag RG80307-NY
    CD68 cDNA ORF Clone, Rat, C-Myc tag RG80307-CM
    CD68 cDNA ORF Clone, Rat, N-Myc tag RG80307-NM
    CD68 qPCR Primer Pairs, Rat RP300283

    CD68 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    CD68 cDNA ORF Clone in Cloning Vector, Mouse MG50730-G
    CD68 cDNA ORF Clone, Mouse, untagged MG50730-UT
    CD68 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50730-ACGLN
    CD68 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50730-ACG
    CD68 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50730-ACR
    CD68 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50730-CF
    CD68 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50730-NF
    CD68 cDNA ORF Clone, Mouse, C-His tag MG50730-CH
    CD68 cDNA ORF Clone, Mouse, N-His tag MG50730-NH
    CD68 cDNA ORF Clone, Mouse, C-HA tag MG50730-CY
    CD68 cDNA ORF Clone, Mouse, N-HA tag MG50730-NY
    CD68 cDNA ORF Clone, Mouse, C-Myc tag MG50730-CM
    CD68 cDNA ORF Clone, Mouse, N-Myc tag MG50730-NM
    CD68 qPCR Primer Pairs, Mouse MP200705

    CD68 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    CD68 cDNA ORF Clone in Cloning Vector, Human HG11192-M
    CD68 cDNA ORF Clone, Human, C-GFPSpark® tag HG11192-ACG
    CD68 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11192-ACGLN
    CD68 cDNA ORF Clone, Human, C-OFPSpark® tag HG11192-ACR
    CD68 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11192-CF
    CD68 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11192-NF
    CD68 cDNA ORF Clone, Human, C-His tag HG11192-CH
    CD68 cDNA ORF Clone, Human, N-His tag HG11192-NH
    CD68 cDNA ORF Clone, Human, C-HA tag HG11192-CY
    CD68 cDNA ORF Clone, Human, N-HA tag HG11192-NY
    CD68 cDNA ORF Clone, Human, C-Myc tag HG11192-CM
    CD68 cDNA ORF Clone, Human, N-Myc tag HG11192-NM
    CD68 qPCR Primer Pairs, Human HP101097
    info info
    添加购物车成功! 添加购物车失败!