|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||HG10457-ACG|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||HG10457-ACR|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||HG10457-CF|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), C-His 标签||HG10457-CH|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||HG10457-CM|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), C-HA 标签||HG10457-CY|
|人 Contactin 2/CNTN2 基因ORF全长cDNA(克隆载体)||HG10457-M|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||HG10457-NF|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), N-His 标签||HG10457-NH|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||HG10457-NM|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体), N-HA 标签||HG10457-NY|
|人 Contactin 2/CNTN2 基因ORF全长cDNA克隆(表达载体)||HG10457-UT|
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-2, also known as CNTN2, is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. The human, rat, and chicken Contactin-2 are alternatively known as TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, respectively. Human Contactin-2 shares approximately 91% and 75% amino acid sequence identity with rat and chicken Contactin-2, respectively. Contactin-2 is expressed by a subset of neuronal populations in the developing central nervous system (CNS) and peripheral nervous system (PNS). Contactin-2 is also expressed by oligodendrocytes and Schwann cells, which are myelinating glial cells of the CNS and PNS, respectively. Contactin-2 may play a role in the formation of axon connections in the developing nervous system. Contactin-2 is also involved in glial tumorigenesis and may provide a potential target for therapeutic intervention. During embryonic development, Contactin-2 interacts either in a homophilic, or heterophilic fashion with various transmembrane proteins.