KK-LC-1 cDNA ORF Clone, Human, N-His tag

Cat: HG13662-NH
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KK-LC-1 cDNA ORF Clone, Human, N-His tag 基本信息
基因
种属
Human
NCBI 参考序列号
参考序列ORF长度
342 bp
描述
Full length Clone DNA of Human chromosome X open reading frame 61 with N terminal His tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-SP-N-His
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
关于 KK-LC-1的更多信息
Entrez Gene ID

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

KK-LC-1 cDNA ORF Clone, Human, N-His tag Alternative Names
CXorf61 cDNA ORF Clone, Human;KK-LC-1 cDNA ORF Clone, Human;KKLC1 cDNA ORF Clone, Human
KK-LC-1 Background Information

The CXorf61 sequence has first been identified by screening of a cDNA library derived from an allogeneic lung cancer cell line with an HLA-B*1507-restricted cytotoxic T lymphocyte (CTL) clone established from a lung cancer patient. In a pilot screen of 20 normal tissues by RT-PCR (normal breast not included) testis tissue was the only one to express CXorf61 transcript. Later, two independent approaches, one mining of massive parallel signature sequencing (MPSS) data, the other providing a survey of CTAs in the Cancer Genome Atlas (TCGA) RNA-seq datasets revealed expression of CXorf61 transcripts in the basal-like subtype of breast cancer. The CXorf61 coding gene is located on chromosome Xq22 and consists of 113 amino acids.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
cancer/testis antigen 83
References
  • Paret C, Simon P, Vormbrock K, et al. CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer. Oncotarget. 2015;6(28):25356-25367.
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