Endothelin A Receptor cDNA ORF Clone, Human, C-Myc tag

Cat: HG14459-CM

Contact us:

215-583-7898
order@sinobiological.com
Distributors

All Endothelin A Receptor Reagents

CRO Services

Product recommended


All Endothelin A Receptor Reagents

Endothelin A Receptor cDNA ORF Clone, Human, C-Myc tag 基本信息

基因

种属
Human
NCBI 参考序列号
参考序列ORF长度
1284 bp
描述
Full length Clone DNA of Human endothelin receptor type A with C terminal Myc tag.

质粒

启动子
Enhanced CMV promoter
载体
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Endothelin A Receptor cDNA ORF Clone, Human, C-Myc tag Alternative Names

ET-A cDNA ORF Clone, Human;ETA cDNA ORF Clone, Human;ETA-R cDNA ORF Clone, Human;ETAR cDNA ORF Clone, Human;ETRA cDNA ORF Clone, Human;hET-AR cDNA ORF Clone, Human

Endothelin A Receptor Background Information

The product of EDNRA, endothelin receptor A, is a G protein-coupled receptor that causes cellular proliferation and contraction (26, 27) of smooth muscle when ligated to endothelin. Polymorphisms in this gene have been associated with variation in vascular phenotypes stemming from vasoconstriction.This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
endothelin receptor type A
References
  • Darrah R, McKone E, O'Connor C, et al. EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity[J]. Physiological genomics, 2010, 41(1): 71-77.
  • info info
    添加购物车成功! 添加购物车失败!