GFAP cDNA ORF Clone, Human, C-Myc tag

Cat: HG12167-CM

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GFAP cDNA ORF Clone, Human, C-Myc tag 基本信息

基因

种属
Human
NCBI 参考序列号
参考序列ORF长度
1344 bp
序列描述
Identical with the Gene Bank Ref. ID sequence.
描述
Full length Clone DNA of Human glial fibrillary acidic protein with C terminal Myc tag.

质粒

启动子
Enhanced CMV promoter
载体
限制性酶切位点
HindIII + XbaI(6kb+1.34kb)
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

GFAP cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

GFAP cDNA ORF Clone, Human, C-Myc tag Validated Images

Cynomolgus CD19/B4/CVID3 Gene Plasmid Map 5621

GFAP cDNA ORF Clone, Human, C-Myc tag Alternative Names

ALXDRD cDNA ORF Clone, Human

GFAP Background Information

GFAP is a cell-specific marker which belongs to the intermediate filament family. It can distinguish astrocytes from other glial cells during development. GFAP is expressed in cells lacking fibronectin. It is a type III intermediate filaments protein which contains three domains: the head, rod and tail domains. GFAP functions in many important entral nervous system (CNS) processes, including cell communication and the functioning of the blood brain barrier. Improper GFAP regulation can cause multiple disorders. Defects in GFAP is related to Alexander disease which is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes.

Full Name
glial fibrillary acidic protein
References
  • Buniatian G, et al., 1998, Biology of the cell. 90(1): 53-61.
  • Chen YS, et al., 2011, Experimental Cell Research. 317(16): 2252-66.
  • Isaacs A, et al., 1998, Genomics. 51(1): 152-4.
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    GFAP cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    GFAP cDNA ORF Clone in Cloning Vector, Human HG12167-G
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    GFAP Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG12167-ACGLN
    GFAP cDNA ORF Clone, Human, N-GFPSpark® tag HG12167-ANG
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    GFAP cDNA ORF Clone, Human, C-His tag HG12167-CH
    GFAP cDNA ORF Clone, Human, N-His tag HG12167-NH
    GFAP cDNA ORF Clone, Human, C-HA tag HG12167-CY
    GFAP cDNA ORF Clone, Human, N-HA tag HG12167-NY
    GFAP cDNA ORF Clone, Human, N-Myc tag HG12167-NM
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