IL1RAPL1 cDNA ORF Clone, Human, C-His tag

Cat: HG10177-CH

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IL1RAPL1 cDNA ORF Clone, Human, C-His tag 基本信息

基因

种属
Human
NCBI 参考序列号
参考序列ORF长度
2091 bp
描述
Full length Clone DNA of Human interleukin 1 receptor accessory protein-like 1 (IL1RAPL1) with C terminal His tag.

质粒

启动子
Enhanced CMV promoter
载体
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

IL1RAPL1 cDNA ORF Clone, Human, C-His tag Alternative Names

IL1R8 cDNA ORF Clone, Human;IL1RAPL cDNA ORF Clone, Human;MRX10 cDNA ORF Clone, Human;MRX21 cDNA ORF Clone, Human;MRX34 cDNA ORF Clone, Human;OPHN4 cDNA ORF Clone, Human;TIGIRR-2 cDNA ORF Clone, Human

IL1RAPL1 Background Information

Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding of an as yet unidentified ligand, a transmembrane region, and an intracellular domain, which is likely to enable signalling via the NFkB pathway. The means of signalling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein. L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1), a protein widely expressed in neurons and the related chromaffin and PC12 cells. IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR). It is suggested to affect human cognitive ability to some extent, especially the memory and concentration capability.

Full Name
interleukin 1 receptor accessory protein-like 1
References
  • Frdric Gambino, et al. (2007) IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation. Proc Natl Acad Sci. 104 (21): 9063-8.
  • Wheway JM, et al. (2003) A complex deletion-inversion-deletion event results in a chimeric IL1RAPL1-dystrophin transcript and a contiguous gene deletion syndrome. J Med Genet. 40: 127-131.
  • IL1RAPL1 cDNA ORF Clone, Mouse, Related Products

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    IL1RAPL1 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    IL1RAPL1 cDNA ORF Clone, Human, untagged HG10177-UT
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    IL1RAPL1 cDNA ORF Clone, Human, C-OFPSpark® tag HG10177-ACR
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    IL1RAPL1 cDNA ORF Clone, Human, C-HA tag HG10177-CY
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    IL1RAPL1 cDNA ORF Clone, Human, C-Myc tag HG10177-CM
    IL1RAPL1 cDNA ORF Clone, Human, N-Myc tag HG10177-NM
    IL1RAPL1 qPCR Primer Pairs, Human HP100245
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