ST2 cDNA ORF Clone, Human, N-His tag

Cat: HG10105-NH
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All ST2 Reagents
CRO Services
Product recommended

All ST2 Reagents
ST2 cDNA ORF Clone, Human, N-His tag 基本信息
基因
种属
Human
NCBI 参考序列号
参考序列ORF长度
987 bp
序列描述
Identical with the Gene Bank Ref. ID sequence.
描述
Full length Clone DNA of Human interleukin 1 receptor-like 1, transcript variant 2 with N terminal His tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-SP-N-His
限制性酶切位点
KpnI + NotI (6kb + 1.03kb)
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
ST2 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

ST2 cDNA ORF Clone, Human, N-His tag Validated Images
Human IL12A / IL-12A Gene Plasmid Map 5646
ST2 cDNA ORF Clone, Human, N-His tag Alternative Names
DER4 cDNA ORF Clone, Human;FIT-1 cDNA ORF Clone, Human;IL1RL1 cDNA ORF Clone, Human;IL33R cDNA ORF Clone, Human;IL‑1 R4 cDNA ORF Clone, Human;ST2 cDNA ORF Clone, Human;ST2L cDNA ORF Clone, Human;ST2V cDNA ORF Clone, Human;T1 cDNA ORF Clone, Human
ST2 Background Information

IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.

Full Name
interleukin 1 receptor-like 1
References
  • Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.
  • Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.
  • info info
    添加购物车成功! 添加购物车失败!