( We provide with LXN qPCR primers for gene expression analysis, HP100069 )
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||HG10211-ACG|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||HG10211-ACR|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), N-GFPSpark 标签||HG10211-ANG|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), N-OFPSpark 标签||HG10211-ANR|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||HG10211-CF|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-His 标签||HG10211-CH|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||HG10211-CM|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-HA 标签||HG10211-CY|
|人 Latexin 基因ORF全长cDNA(克隆载体)||HG10211-M|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||HG10211-M-F|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||HG10211-NF|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), N-His 标签||HG10211-NH|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||HG10211-NM|
|人 Latexin 基因ORF全长cDNA克隆(表达载体), N-HA 标签||HG10211-NY|
|人 Latexin 基因ORF全长cDNA克隆(表达载体)||HG10211-UT|
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI and LXN, is a cytoplasm protein which belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite of the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. In addition, Latexin is also implicated in Alzheimer's disease.