MAP1LC3A cDNA ORF Clone, Human, C-His tag

Cat: HG14322-CH
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MAP1LC3A cDNA ORF Clone, Human, C-His tag 基本信息
基因
种属
Human
NCBI 参考序列号
参考序列ORF长度
366 bp
描述
Full length Clone DNA of Human microtubule-associated protein 1 light chain 3 alpha with C terminal His tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-C-His
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

MAP1LC3A cDNA ORF Clone, Human, C-His tag Alternative Names
ATG8E cDNA ORF Clone, Human;LC3 cDNA ORF Clone, Human;LC3A cDNA ORF Clone, Human;MAP1ALC3 cDNA ORF Clone, Human;MAP1BLC3 cDNA ORF Clone, Human
MAP1LC3A Background Information

LC3A, also known as MAP1LC3A, is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. As a light chain subunit, MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.

Full Name
microtubule-associated protein 1 light chain 3 alpha
References
  • He H., et al.,(2003), Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J. Biol. Chem. 278:29278-29287.
  • Deloukas P., et al., (2001), The DNA sequence and comparative analysis of human chromosome 20.Nature 414:865-871.
  • Bechtel S., et al.,(2007), The full-ORF clone resource of the German cDNA consortium.BMC Genomics 8:399-399.
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