|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||HG11372-ACG|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||HG11372-ACR|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||HG11372-CF|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), C-His 标签||HG11372-CH|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||HG11372-CM|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), C-HA 标签||HG11372-CY|
|人 MDGA2 基因ORF全长cDNA(克隆载体)||HG11372-M|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||HG11372-NF|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), N-His 标签||HG11372-NH|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||HG11372-NM|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体), N-HA 标签||HG11372-NY|
|人 MDGA2 基因ORF全长cDNA克隆(表达载体)||HG11372-UT|
Mouse MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2 and MAMDC1, is a cell membrane protein which contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated, and that MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance.